DNA Binding Motif

Accessions: ETV5_EOMES_1 (HumanTF2 1.0)
Names: ETV5_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 29
Consensus: rrGTGtkrdbskgrgkTsrCrsmGGAwgy
Weblogo:
PSSM: P0 A C G T
01 160 43 113 75 r
02 74 49 106 44 r
03 29 25 273 21 G
04 12 82 33 273 T
05 9 12 273 12 G
06 46 65 46 116 t
07 3 64 131 75 k
08 147 19 71 36 r
09 93 33 74 73 d
10 43 79 82 69 b
11 43 73 96 62 s
12 55 37 96 85 k
13 60 52 95 66 g
14 75 65 101 32 r
15 40 57 108 68 g
16 57 64 77 76 k
17 7 46 25 195 T
18 53 103 96 21 s
19 147 18 126 75 r
20 0 273 36 33 C
21 158 2 115 0 r
22 112 273 150 10 s
23 117 273 11 2 m
24 0 0 273 7 G
25 0 0 273 5 G
26 273 2 10 0 A
27 118 20 20 155 w
28 51 83 190 34 g
29 40 84 42 108 y
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
ETV5_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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