DNA Binding Motif

Accessions: MA0043.4 (JASPAR 2024)
Names: HLF
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 9
Consensus: TTATGYAAy
Weblogo:
PSSM: P0 A C G T
01 295 242 148 23739 T
02 162 96 895 23271 T
03 22746 125 1344 209 A
04 197 1548 253 22426 T
05 2418 112 21705 189 G
06 369 17203 199 6653 Y
07 24156 122 48 98 A
08 24055 67 189 113 A
09 1399 13237 3300 6488 y
Type: Heterodimer
Binding TFs: Q16534 (Basic region leucine zipper)
Q16534
Binding Sites: MA0043.4.14
MA0043.4.15 / MA0043.4.20 / MA0043.4.5
MA0043.4.18 / MA0043.4.7 / MA0043.4.8
MA0043.4.6
MA0043.4.10 / MA0043.4.16 / MA0043.4.19
MA0043.4.1 / MA0043.4.2
MA0043.4.11 / MA0043.4.12 / MA0043.4.13 / MA0043.4.4
MA0043.4.17
MA0043.4.3
MA0043.4.9
Publications: Hunger S. P., Brown R., Cleary M. L. DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF. Mol. Cell. Biol. 14:5986-5996 (1994). [Pubmed]

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