DNA Binding Motif

						

			
Accessions: TFAP2C_HES7_2 (HumanTF2 1.0)

			
Names: TFAP2C_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: srCACGyGccywtssCCysrGGs
Weblogo: 
PSSM: P0      A      C      G      T
01   4433   6529  10891   3491      s
02   7198   4924  11082   2139      r
03   1097  25343    591    497      C
04  18760    878   6583   1338      A
05    327  25343    209   2783      C
06   2202    331  25343    263      G
07   1113   8494    858  16850      y
08   1079   2385  25343   1998      G
09   3793  10524   4766   6260      c
10   4997  11054   4078   5214      c
11   4842   8394   5419   6689      y
12   8044   5580   5193   6527      w
13   4956   5708   4828   9851      t
14   5703   6340   7375   5925      s
15   2760   8633  16711   1199      s
16    440  25343   2964    193      C
17    168  25343    382   5308      C
18   1592   7839   4835  11077      y
19   3924   8724   8452   4243      s
20  10525   5598   7399   1821      r
21   8731   1651  25343    583      G
22    630    430  25343     89      G
23   1163  14746  10597   1588      s
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
TFAP2C_TF1 (Transcription factor AP-2)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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