DNA Binding Motif

						

			
Accessions: FOXJ2_HOXB13_2_3 (HumanTF2 1.0), UN0533.1 (JASPAR 2024)

			
Names: FOXJ2_HOXB13, FOXJ2::HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: rTAAACwwATWAAa
Weblogo: 
PSSM: P0      A      C      G      T
01    311     71    453     68      r
02      0    139    126    763      T
03    763    184     33     12      A
04    763    132     46     64      A
05    763     33    145      0      A
06     16    763     42      0      C
07    399    130     67    364      w
08    296    175      0    296      w
09    763     13    245     19      A
10      0     24    134    763      T
11    565     22      0    198      W
12    763      2      0      0      A
13    763     28      0     18      A
14    763    224    153    169      a
Type: Heterodimer
Binding TFs: Q9P0K8 (Fork head domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
FOXJ2_TF1 (Fork head domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Q9P0K8
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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