DNA Binding Motif

						

			
Accessions: 1c0w_ABCD (3D-footprint 20231221)

			
Names: DIPHTHERIA TOXIN REPRESSOR
Organisms: Corynebacterium diphtheriae, strain ATCC 700971 / NCTC 13129 / Biotype gravis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
Length: 15
Consensus: TnAGGTAGCCTACCT
Weblogo: 
PSSM: P0      A      C      G      T
01     10      6      5     75      T
02     24     24     24     24      n
03     75      5      6     10      A
04      5      5     75     11      G
05      0      0     96      0      G
06      0      0      0     96      T
07     96      0      0      0      A
08      5      5     80      6      G
09      0     96      0      0      C
10      0     96      0      0      C
11      0      0      0     96      T
12     96      0      0      0      A
13      0     96      0      0      C
14      1     85      5      5      C
15      6      5      5     80      T
Type: Heterodimer
Binding TFs: 1c0w_A (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain)
1c0w_B (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, FeoA domain)
1c0w_C (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain)
1c0w_D (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain)
Binding Sites: 1c0w_E
1c0w_F
			
Publications: Pohl E, Holmes R.K, Hol W.G. Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. Journal of molecular biology 292:653-67 (1999). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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