DNA Binding Motif

Accessions: 1qp9_AB (3D-footprint 20231221)
Names: CYP1(HAP1-PC7) ACTIVATORY PROTEIN
Organisms: Saccharomyces cerevisiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURE OF HAP1-PC7 COMPLEXED TO THE UAS OF CYC7
Length: 18
Consensus: CGCnnnTATCGCnnnTAG
Weblogo:
PSSM: P0 A C G T
01 1 90 5 0 C
02 5 5 85 1 G
03 10 74 2 10 C
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 0 0 0 96 T
08 96 0 0 0 A
09 0 0 0 96 T
10 5 86 5 0 C
11 0 0 96 0 G
12 5 69 17 5 C
13 24 24 24 24 n
14 24 24 24 24 n
15 24 24 24 24 n
16 5 5 0 86 T
17 80 5 10 1 A
18 0 5 90 1 G
Type: Heterodimer
Binding TFs: 1qp9_A (Fungal Zn(2)-Cys(6) binuclear cluster domain)
1qp9_B (Fungal Zn(2)-Cys(6) binuclear cluster domain)
Binding Sites: 1qp9_E
1qp9_F
Publications: Lukens A.K, King D.A, Marmorstein R. Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation. Nucleic acids research 28:3853-63 (2000). [Pubmed]

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