DNA Binding Motif

						

			
Accessions: HOXB2_PITX1_2_3_4 (HumanTF2 1.0)

			
Names: HOXB2_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: TaATkrsrrGGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01     64     15     10    219      T
02    219     37     63     52      a
03    219      2      0      0      A
04     11     24      3    219      T
05     16     27    117    101      k
06    130      3     89      4      r
07     49     56     61     53      s
08    117     13    102     36      r
09     57     30     81     52      r
10     17     18    219     18      G
11      0      3    219      0      G
12    219     24     25     18      A
13      5      9     12    219      T
14     20     15     22    219      T
15    219      1     10     16      A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
PITX1_TF1 / PITX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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