DNA Binding Motif

Accessions: HOXB13_TBX3_2 (HumanTF2 1.0)
Names: HOXB13_TBX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: cymrTAAAmsTcaCACcy
Weblogo:
PSSM: P0 A C G T
01 106 209 95 16 c
02 39 201 27 157 y
03 156 149 19 101 m
04 292 16 134 0 r
05 0 4 5 425 T
06 425 0 38 118 A
07 425 13 0 43 A
08 425 8 13 7 A
09 151 129 66 80 m
10 87 120 132 87 s
11 53 66 55 425 T
12 89 190 90 56 c
13 425 50 139 45 a
14 12 425 12 29 C
15 425 18 150 17 A
16 0 425 24 0 C
17 85 319 72 107 c
18 97 124 26 179 y
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
TBX3_TF2 (T-box)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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