DNA Binding Motif

Accessions: HOXB13_EOMES_2 (HumanTF2 1.0)
Names: HOXB13_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: cymrTwAawtmaCAccy
Weblogo:
PSSM: P0 A C G T
01 85 218 99 60 c
02 61 204 34 163 y
03 248 215 31 149 m
04 329 15 133 45 r
05 45 55 3 462 T
06 462 27 33 201 w
07 462 16 10 59 A
08 462 90 30 146 a
09 142 88 113 119 w
10 98 126 56 462 t
11 184 278 87 87 m
12 462 89 173 96 a
13 32 462 30 35 C
14 462 22 140 19 A
15 133 462 77 32 c
16 105 192 56 108 c
17 87 117 46 212 y
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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