DNA Binding Motif

						

			
Accessions: 1ozj_AB (3D-footprint 20231221)

			
Names: SMAD 3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution
Length: 9
Consensus: GtCTAGaCA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02     16     13     13     54      t
03      0     96      0      0      C
04      0      0      0     96      T
05     96      0      0      0      A
06      0      0     96      0      G
07     57     13     13     13      a
08      0     96      0      0      C
09     96      0      0      0      A
Type: Heterodimer
Binding TFs: 1ozj_A (MH1 domain)
1ozj_B (MH1 domain)
Binding Sites: 1ozj_C
1ozj_D
			
Publications: Chai J, Wu J.W, Yan N, Massagué J, Pavletich N.P, Shi Y. Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding. The Journal of biological chemistry 278:20327-31 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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