DNA Binding Motif

						

			
Accessions: ERF_TBX21_1 (HumanTF2 1.0)

			
Names: ERF_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 29
Consensus: agGTGtgaagwrvkgktcaCrCCGGAArw
Weblogo: 
PSSM: P0      A      C      G      T
01    744    332    411    295      a
02    582    515    970    345      g
03    136    264   1752    189      G
04    119    323    283   1689      T
05     84    175   1693    198      G
06    321    561    508   1466      t
07    313    439    819    213      g
08   1601    283    382    138      a
09    900    348    382    154      a
10    445    348    628    363      g
11    464    292    441    587      w
12    564    363    462    395      r
13    460    468    467    387      v
14    283    234    687    579      k
15    314    338    709    422      g
16    198    401    617    567      k
17    114    313    237   1119      t
18    409    781    374    220      c
19   1029    126    290    339      a
20     64   1569     68     83      C
21   1125     48    551     59      r
22    165   1706    188    117      C
23    445   1624    148      0      C
24     43     41   1780     36      G
25     25     46   1780     23      G
26   1746     63     64    109      A
27   1624    211     44    496      A
28    470    363    890     60      r
29    461    387    441    494      w
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ERF_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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