DNA Binding Motif

Accessions: UP00018A_1 (UniPROBE 20160601)
Names: AI385587, interferon regulatory factor 4, IRF-4, Irf4, LSIRF, Lymphocyte-specific interferon regulatory factor, NF-EM5, PU.1 interaction partner, Spip, Transcriptional activator PIP
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 15
Consensus: mrwayCGAAACyrma
Weblogo:
PSSM: P0 A C G T
01 0.30 0.39 0.16 0.14 m
02 0.26 0.11 0.47 0.16 r
03 0.31 0.08 0.17 0.44 w
04 0.66 0.04 0.05 0.24 a
05 0.18 0.28 0.07 0.47 y
06 0.01 0.89 0.01 0.09 C
07 0.01 0 0.98 0 G
08 0.99 0.01 0.01 0 A
09 0.93 0 0 0.06 A
10 0.99 0 0 0.01 A
11 0.02 0.95 0.03 0.01 C
12 0.03 0.57 0.02 0.38 y
13 0.40 0.13 0.32 0.15 r
14 0.33 0.28 0.20 0.20 m
15 0.51 0.14 0.17 0.19 a
Binding TFs: UP00018A (Interferon regulatory factor transcription factor)
Binding Sites: AACGAAAC
AAGTTTCG
ACCGAAAC
ACGAAACC
AGTTTCGA
AGTTTCGC
AGTTTCGG
ATCGAAAC
CAGTTTCG
CCGAAACC
CGAAACCA
CGAAACCC
CGAAACCG
CGAAACTA
CGAAACTC
GGTTTCGA
GTTTCGAA
GTTTCGGA
TAGTTTCA
TTTCGAAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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