DNA Binding Motif

						

			
Accessions: SPDEF_methyl_1 (HT-SELEX2 May2017)

			
Names: SPDEF
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 12
Consensus: rAmCAGGATgyd
Weblogo: 
PSSM: P0      A      C      G      T
01   2364   1726   2584   1437      r
02   8112    361    947   2226      A
03   4530   3582   2178    539      m
04    404   8112    294    582      C
05   8112   2721     60      0      A
06      0     35   8112      0      G
07      0      0   8112      0      G
08   8112      0      0      4      A
09    347   1835     11   8112      T
10   3144   1147   8112    195      g
11    326   4199    232   8112      y
12   2283    905   2635   2289      d
Binding TFs: SPDEF (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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