DNA Binding Motif

						

			
Accessions: HOXA3_PAX5 (HumanTF2 1.0)

			
Names: HOXA3_PAX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: tcATTAGTCACGCwTsrcTr
Weblogo: 
PSSM: P0      A      C      G      T
01     29    134    119    289      t
02    109    161     99    116      c
03    469     17      6     11      A
04      4      5      0    485      T
05      7     66      0    460      T
06    483     15      9     17      A
07      2      5    481      7      G
08     32     49     14    469      T
09      4    464      0    115      C
10    464     44     12     14      A
11     16    446      4     86      C
12      0      9    481      5      G
13      4    427    129      5      C
14    210     14     62    248      w
15     11     81     12    446      T
16      0    156    329      0      s
17    329      9    151      0      r
18     98    216    117     54      c
19     15    127     34    440      T
20    175     14    293     78      r
Type: Heterodimer
Binding TFs: PAX5_TF1 / PAX5_TF2 ('Paired box' domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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