DNA Binding Motif

Accessions: UP00509A_1 (UniPROBE 20160601)
Names: CG3871, D-six4, Dmel\CG3871, Dsix4, Six4, six4/5
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: ywmarrywTGACACCymbhwrw
Weblogo:
PSSM: P0 A C G T
01 0.09 0.43 0.18 0.30 y
02 0.37 0.09 0.10 0.43 w
03 0.54 0.27 0.03 0.16 m
04 0.45 0.17 0.18 0.21 a
05 0.30 0.20 0.26 0.24 r
06 0.43 0.12 0.30 0.15 r
07 0.19 0.40 0.14 0.26 y
08 0.56 0.05 0.10 0.29 w
09 0.03 0.04 0.01 0.92 T
10 0.02 0 0.95 0.02 G
11 0.99 0 0 0.01 A
12 0.01 0.85 0.01 0.14 C
13 0.98 0.02 0 0.01 A
14 0.01 0.99 0 0 C
15 0 0.95 0.01 0.03 C
16 0.16 0.30 0.13 0.41 y
17 0.34 0.31 0.22 0.12 m
18 0.14 0.28 0.31 0.26 b
19 0.33 0.26 0.12 0.29 h
20 0.33 0.20 0.20 0.27 w
21 0.30 0.15 0.42 0.14 r
22 0.36 0.21 0.10 0.34 w
Binding TFs: UP00509A (Homeobox domain, Homeobox KN domain, Homeodomain leucine-zipper encoding, Homez)
Binding Sites: AAGATATC
AATGATAC
AGATATCA
AGGTATCA
AGGTGTCA
AGTATCAT
ATGACACC
ATGATACC
ATGATCCC
CGGTGTCA
CTGACACC
GGGTATCA
GGGTGTCA
GGTATCAA
GGTATCAC
GGTGTCAA
GGTGTCAC
GTATCATA
TGACACCA
GACACCCC
Publications: Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed]

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