DNA Binding Motif

Accessions: GCM1_ONECUT2_1 (HumanTF2 1.0)
Names: GCM1_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rTGcGGGwAATCGATr
Weblogo:
PSSM: P0 A C G T
01 1403 358 635 119 r
02 137 253 205 2038 T
03 485 53 2038 26 G
04 317 2038 296 726 c
05 85 58 2038 49 G
06 4 0 2038 6 G
07 0 0 2038 35 G
08 810 361 218 649 w
09 1658 22 265 93 A
10 2038 16 122 81 A
11 31 66 35 2038 T
12 7 2038 0 53 C
13 530 110 2038 83 G
14 2038 24 83 107 A
15 23 24 52 2038 T
16 1262 428 777 479 r
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
ONECUT2_TF2 (Homeobox domain, CUT domain)
ONECUT2_Full (Homeobox domain, CUT domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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