DNA Binding Motif

						

			
Accessions: THRB_methyl_6 (HT-SELEX2 May2017)

			
Names: THRB
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 19
Consensus: rTGWCCTyRCrTGWCCTyR
Weblogo: 
PSSM: P0      A      C      G      T
01    240     24    263    118      r
02      0     30      4    615      T
03     54     33    645      0      G
04    645      0      0    238      W
05      5    645     19     16      C
06      8    645     32     17      C
07      1      0      9    645      T
08      0    369     60    236      y
09    475      0    168      5      R
10     34    458     43    111      C
11    207     20    406     11      r
12      0    111      0    533      T
13      0      0    645     16      G
14    645      0      0    254      W
15      0    645      4      0      C
16      3    645      3      5      C
17      0      0      0    645      T
18      0    380     37    264      y
19    465      0    201      0      R
Binding TFs: THRB (Zinc finger, C4 type (two domains))
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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