DNA Binding Motif

						

			
Accessions: 6lc1_GJ (3D-footprint 20231221)

			
Names: Nuclear receptor subfamily 4 group A member 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter
Length: 22
Consensus: TGnCATnTgnnnGTAnATAnnA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      4      4     84      4      G
03     24     24     24     24      n
04      0     96      0      0      C
05     96      0      0      0      A
06      0      0      0     96      T
07     24     24     24     24      n
08      4      4      7     81      T
09     14      9     64      9      g
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13      9      9     69      9      G
14      0      0      0     96      T
15     96      0      0      0      A
16     24     24     24     24      n
17     69      9      9      9      A
18      0      0      0     96      T
19     96      0      0      0      A
20     24     24     24     24      n
21     24     24     24     24      n
22     96      0      0      0      A
Type: Heterodimer
Binding TFs: 6lc1_G (Zinc finger, C4 type (two domains))
6lc1_J (Zinc finger, C4 type (two domains))
Binding Sites: 6lc1_I
6lc1_L
			
Publications: Jiang L, Wei H, Yan N, Dai S, Li J, Qu L, Chen X, Guo M, Chen Z, Chen Y. Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter. Biochem Biophys Res Commun 523:1-5 (2020). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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