DNA Binding Motif

						

			
Accessions: HOXD12_TBX21_2_3 (HumanTF2 1.0)

			
Names: HOXD12_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: yvrCACsTCrTWAw
Weblogo: 
PSSM: P0      A      C      G      T
01    156    524    213   1163      y
02    600    428    476    182      v
03    794     87    892    252      r
04      0   1686      0    196      C
05   1686     56    125     17      A
06     78   1686    200      0      C
07    502    965    721     84      s
08      7     43      8   1686      T
09    270   1686      3    280      C
10   1215     16   1686     95      r
11     20     14     18   1686      T
12   1259      9      0    427      W
13   1686      7     14    121      A
14   1686    684    326    953      w
Type: Heterodimer
Binding TFs: HOXD12_TF1 (Homeobox domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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