DNA Binding Motif

						

			
Accessions: GCM1_CEBPB_2 (HumanTF2 1.0)

			
Names: GCM1_CEBPB
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: rTGcGGGyrgrkrTTGCGYAAy
Weblogo: 
PSSM: P0      A      C      G      T
01   2309    292    884     23      r
02     99     60     69   2601      T
03    513     68   2088     62      G
04    511   1927    674    154      c
05    111    254   2601    308      G
06     17     53   2601    126      G
07     23     26   2601     38      G
08    132   1267    337    865      y
09    655    598    765    583      r
10    376    475   1198    553      g
11    658    368   1151    424      r
12    450    612    659    880      k
13   1253    240   1096     13      r
14      0      0      2   2601      T
15      0      2    123   2601      T
16    616     10   1986      1      G
17      0   2601      0    113      C
18     22      0   2601      0      G
19      0   1905      3    696      Y
20   2601    130      1      7      A
21   2601      3      0      2      A
22     21   1017    333   1230      y
Type: Heterodimer
Binding TFs: CEBPB_TF2 (bZIP transcription factor, Basic region leucine zipper)
GCM1_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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