DNA Binding Motif

Accessions: CLOCK_TBX3 (HumanTF2 1.0)
Names: CLOCK_TBX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: sGTGTgrdysgCACGTG
Weblogo:
PSSM: P0 A C G T
01 381 1051 1448 124 s
02 43 121 1448 35 G
03 28 351 65 1448 T
04 62 33 1448 29 G
05 153 189 77 1448 T
06 272 447 1448 656 g
07 629 117 457 245 r
08 435 134 391 487 d
09 346 439 245 418 y
10 343 428 542 135 s
11 242 359 680 167 g
12 65 1448 4 0 C
13 1448 0 68 28 A
14 0 1448 3 82 C
15 150 0 1448 4 G
16 26 6 10 1448 T
17 0 28 1448 112 G
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
TBX3_TF2 (T-box)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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