DNA Binding Motif

						

			
Accessions: TEAD4_PITX1_1 (HumanTF2 1.0)

			
Names: TEAD4_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rCATwcywraGGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    161     19    169     23      r
02     59    330     34      0      C
03    330      0      4      0      A
04      8      0      2    330      T
05    182     10     42    148      w
06     69    330     13     75      c
07     43    121     28    138      y
08     86     25     64    155      w
09    137     44     95     54      r
10    152     29     69     79      a
11     63     44    330     19      G
12     34     31    330     29      G
13    330     80      0     48      A
14     17      4     10    330      T
15     13     39     18    330      T
16    330     25      0     26      A
Type: Heterodimer
Binding TFs: PITX1_TF1 / PITX1_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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