DNA Binding Motif

						

			
Accessions: ERF_MAX (HumanTF2 1.0), UN0507.1 (JASPAR 2024)

			
Names: ERF_MAX, ERF::MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: aCCGGAAaCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   4520    903   1911   1328      a
02    649   5350   1081    137      C
03    966   6432    115     64      C
04     25    107   6432     11      G
05     40     66   6432     44      G
06   6432     70      0     39      A
07   6432     84     19    360      A
08   3731   1154   1494     53      a
09      4   6432      8     28      C
10   6432     49     23     17      A
11     12   6432     32     71      C
12     72      9   6432      0      G
13    171    282     65   6432      T
14     28      7   6432     24      G
15    904   1833   2245   1450      s
Type: Heterodimer
Binding TFs: P61244 (Helix-loop-helix DNA-binding domain)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
ERF_TF1 (Ets-domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
P61244
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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