DNA Binding Motif

Accessions: 5xxp_AB (3D-footprint 20231221)
Names: LysR-type regulatory protein
Organisms: Cupriavidus necator, Cupriavidus necator (Alcaligenes eutrophus)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of CbnR_DBD-DNA complex
Length: 19
Consensus: TtACgnnnnncGTAAnnnT
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 21 15 0 60 t
03 96 0 0 0 A
04 0 96 0 0 C
05 18 21 51 6 g
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 18 51 21 6 c
12 0 0 96 0 G
13 0 0 3 93 T
14 96 0 0 0 A
15 75 0 0 21 A
16 24 24 24 24 n
17 24 24 24 24 n
18 24 24 24 24 n
19 0 0 0 96 T
Binding TFs: 5xxp_A / 5xxp_B (Bacterial regulatory helix-turn-helix protein, lysR family)
Binding Sites: 5xxp_E
5xxp_F
Publications: Koentjoro MP, Adachi N, Senda M, Ogawa N, Senda T. Crystal structure of the DNA-binding domain of the LysR-type transcriptional regulator CbnR in complex with a DNA fragment of the recognition-binding site in the promoter region. FEBS J 285:977-989 (2018). [Pubmed]

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