DNA Binding Motif

						

			
Accessions: TEAD4_DLX3_1 (HumanTF2 1.0)

			
Names: TEAD4_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rCATwCCrhsyaATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    475     16    628     25      r
02    203   1103     80      0      C
03   1103      6    145      6      A
04     14      2      7   1103      T
05    869     12    266   1103      w
06      3   1103     58     30      C
07    116   1103     32    332      C
08    391    136    307    269      r
09    290    326    198    289      h
10    249    301    391    162      s
11    148    702     90    401      y
12   1103    497    346    172      a
13   1103    184     59     35      A
14     20      0      7   1103      T
15     64    142     53   1103      T
16   1103     40    251    177      A
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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