DNA Binding Motif

						

			
Accessions: TEAD4_FIGLA_2_3 (HumanTF2 1.0)

			
Names: TEAD4_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: CATwCCacgvhatsymCAssTGs
Weblogo: 
PSSM: P0      A      C      G      T
01    713   2907    227     28      C
02    940     14     21     25      A
03     37     25      0    940      T
04    601     47    389    940      w
05     71    940     40     48      C
06     88    940     31    187      C
07    439    103    224    173      a
08    189    317    231    203      c
09    155    192    471    123      g
10    251    305    268    116      v
11    346    316     37    241      h
12    566    166     77    131      a
13     27    183    166    564      t
14     26    248    442    225      s
15    210    344     86    299      y
16    300    411    194     35      m
17      0    940      0      7      C
18    940     24      0     12      A
19      0    526    414      0      s
20     11    518    423      8      s
21      9     18      8    940      T
22      9     11    940      0      G
23     94    253    373    221      s
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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