DNA Binding Motif

						

			
Accessions: HOXB2_TBX3 (HumanTF2 1.0), UN0565.1 (JASPAR 2024)

			
Names: HOXB2_TBX3, HOXB2::TBX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 12
Consensus: rGGTGTTAATkr
Weblogo: 
PSSM: P0      A      C      G      T
01    934     86    433    158      r
02    127    151    934     46      G
03      0     14    934     20      G
04      0    125      3    934      T
05      2      0    934      0      G
06     52    273     45    934      T
07    124     83     91    934      T
08    934      5    265     12      A
09    934     13     11     10      A
10      9    117    117    934      T
11     53     96    596    337      k
12    242    114    391    187      r
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
TBX3_TF2 (T-box)
P14652 (Homeobox domain)
P14652
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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