DNA Binding Motif

Accessions: ELK1_EOMES_2_3 (HumanTF2 1.0)
Names: ELK1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: tmrCACCGGAAgy
Weblogo:
PSSM: P0 A C G T
01 1266 2514 1422 9374 t
02 2443 4353 1780 798 m
03 5841 875 3533 1433 r
04 693 9374 768 552 C
05 9374 135 3140 152 A
06 455 9374 780 98 C
07 1022 9374 47 12 C
08 19 0 9374 8 G
09 0 12 9374 45 G
10 9374 27 5 106 A
11 9374 306 20 2233 A
12 2594 2124 9374 380 g
13 938 2544 1610 4281 y
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
EOMES_TF2 (T-box)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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