DNA Binding Motif

						

			
Accessions: RFX3_HES7 (HumanTF2 1.0)

			
Names: RFX3_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: TrGCAACssrCACGyGcs
Weblogo: 
PSSM: P0      A      C      G      T
01     35    122     26   1447      T
02    680     88    950     17      r
03    325    124   1630     34      G
04    239   1630     38    260      C
05   1630     32    134     26      A
06   1630     40     49     61      A
07     31   1630     21     50      C
08    189    561    765    115      s
09    279    440    644    267      s
10    484    275    817     53      r
11     54   1630     47     17      C
12   1245      0    385     64      A
13     20   1630      9    106      C
14    188     65   1630     19      G
15     34    556     34   1074      y
16     51     49   1630     57      G
17    152    963    213    301      c
18    183    532    713    201      s
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
RFX3_TF1 (RFX DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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