DNA Binding Motif

						

			
Accessions: E2F3_EOMES (HumanTF2 1.0)

			
Names: E2F3_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: argYGykAtGGCGCstTmrCrcyt
Weblogo: 
PSSM: P0      A      C      G      T
01    295     56    119     87      a
02    171    106    159    121      r
03    157     52    558    143      g
04      0    145      0    413      Y
05     33      0    558     29      G
06     99    197     18    243      y
07     97     25    216    219      k
08    420     12     67     59      A
09    131     63    110    254      t
10     84     29    558     90      G
11      4     20    558      2      G
12     12    558      0     13      C
13     14      0    558      0      G
14      0    558     32      2      C
15     17    267    290     75      s
16    117     61    100    279      t
17     37     79     10    431      T
18    229    174     88     66      m
19    178     54    192    134      r
20     14    558      6     14      C
21    360     22    198     27      r
22    150    558    223    234      c
23    116    159    133    150      y
24     84     95     95    283      t
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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