DNA Binding Motif

						

			
Accessions: MA0865.2 (JASPAR 2024)

			
Names: E2F8
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: CAP-SELEX
Length: 12
Consensus: tTCCCGCcAwwa
Weblogo: 
PSSM: P0      A      C      G      T
01    155    321     78   1012      t
02    405    237     96   1566      T
03     78   1566    170     16      C
04     12   1566    374      0      C
05     44   1566      6     13      C
06     39      7   1566     13      G
07      1   1566     26     15      C
08    104   1566    537    274      c
09   1566    128     95     97      A
10   1566    966    461   1061      w
11   1566    457    460    840      w
12    819    212    149    386      a
Type: Heterodimer
Binding TFs: A0AVK6 (E2F/DP family winged-helix DNA-binding domain)
A0AVK6
			
Publications: Rabinovich A, Jin VX, Rabinovich R, Xu X, Farnham PJ. E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites. Genome Res 18:1763-77 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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