DNA Binding Motif

						

			
Accessions: ETV2_EVX1 (HumanTF2 1.0)

			
Names: ETV2_EVX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: asCGGwAATkrymrTTwm
Weblogo: 
PSSM: P0      A      C      G      T
01    731    319    395    195      a
02    337    669    458     96      s
03    308   1126     46      7      C
04      3      0   1126      0      G
05      0     33   1126     16      G
06    574     11      0    552      w
07   1126      0     97     41      A
08   1126      7     76      0      A
09     71    148     70   1126      T
10    202    142    455    327      k
11    294    193    454    185      r
12    132    456    227    312      y
13    510    815    336    312      m
14   1126     31    499     55      r
15     99     31      0   1126      T
16    169    258     31   1126      T
17   1126     25     56    564      w
18    289    416    239    183      m
Type: Heterodimer
Binding TFs: EVX1_TF1 / EVX1_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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