DNA Binding Motif

						

			
Accessions: 6xwh_C (3D-footprint 20231221)

			
Names: Retinoic acid receptor RXR-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the Human RXR DNA-Binding Domain Homodimer Bound to the Human Hoxb13 DR0 Response Element
Length: 5
Consensus: GGyCr
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     96      0      G
03     12     24     12     48      y
04      0     96      0      0      C
05     48     12     24     12      r
Binding TFs: 6xwh_C (Zinc finger, C4 type (two domains))
Binding Sites: 6xwh_A
6xwh_B
			
Publications: Osz J, McEwen AG, Bourguet M, Przybilla F, Peluso-Iltis C, Poussin-Courmontagne P, Mély Y, Cianférani S, Jeffries CM, Svergun DI, Rochel N. Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res 48:9969-9985 (2020). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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