DNA Binding Motif

						

			
Accessions: GCM1_SPDEF_2 (HumanTF2 1.0)

			
Names: GCM1_SPDEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: rTGvkGGCGGAygbsrsaTCCGgb
Weblogo: 
PSSM: P0      A      C      G      T
01    229     56    264     29      r
02     43     35     99    477      T
03    130     30    375     14      G
04    190    228    206     37      v
05     40     16    285    218      k
06      1      9    521      5      G
07     11      0    513      7      G
08     21    504      7     12      C
09      0      5    512     12      G
10     16      0    513     20      G
11    514      8      0     39      A
12    102    156     40    219      y
13     94     58    274     91      g
14     29    137    132    220      b
15    105    182    145     86      s
16    138     46    250     83      r
17     46    226    158     87      s
18    425     33    163    143      a
19     14     50     28    511      T
20     32    506     18     24      C
21      3    509      0     19      C
22     15      2    452     49      G
23      8    108    295    107      g
24     56    151    179    132      b
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
SPDEF_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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