DNA Binding Motif

						

			
Accessions: HOXB2_SOX15_2_3_4 (HumanTF2 1.0)

			
Names: HOXB2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: symATtarsmamaCAAtr
Weblogo: 
PSSM: P0      A      C      G      T
01     20     79     54     33      s
02     56     90     30     96      y
03     94     91     26     10      m
04    186     10     30     18      A
05     10     21     10    186      T
06     25     63     18    186      t
07    186     28     64     22      a
08     51     39     67     30      r
09     21     65     56     44      s
10     68     48     28     42      m
11     78     33     42     33      a
12     76     64     41      5      m
13    186     32     27     45      a
14      0    186     33     45      C
15    186     25      8      7      A
16    186      4     15     47      A
17     63     32      0    186      t
18     74      3    111     30      r
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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