DNA Binding Motif

						

			
Accessions: 1bf5_A (3D-footprint 20231221)

			
Names: SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
Length: 8
Consensus: GTAanngC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0      0     96      T
03     96      0      0      0      A
04     54     13     16     13      a
05     24     24     24     24      n
06     24     24     24     24      n
07     13     13     54     16      g
08      0     96      0      0      C
Binding TFs: 1bf5_A (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain)
Binding Sites: 1bf5_B
1bf5_C
			
Publications: Chen X, Vinkemeier U, Zhao Y, Jeruzalmi D, Darnell J.E, Kuriyan J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 93:827-39 (1998). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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