DNA Binding Motif

						

			
Accessions: RUNX2_2 (HT-SELEX2 May2017)

			
Names: RUNX2
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 20
Consensus: cwaACCRCAawAACCrCAam
Weblogo: 
PSSM: P0      A      C      G      T
01   2454   5301   2293   2744      c
02   5703   3370    725   5964      w
03  10695   1833   3426   1640      a
04  12557    630    368     61      A
05     43  12781     19     19      C
06     48  12788     21     27      C
07   4561     96  11528    128      R
08     36  12782      9     24      C
09  12308    358   1055    309      A
10   7299   1122   2356   2015      a
11   7583    746    662   3802      w
12  10792    241    520   1240      A
13  12617    456    303     79      A
14     67  12780     37     31      C
15     38  12777     43     23      C
16   5345    109  11397    182      r
17     69  12778     41     55      C
18  12375    364    970    290      A
19  10287   2636   3646   2120      a
20   3822   4240   2501   2229      m
Binding TFs: RUNX2 (Runt domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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