DNA Binding Motif

						

			
Accessions: UP00399A_1 (UniPROBE 20160601)

			
Names: "POU domain, "POU2F1, class 2, NF-A1, Oct-1, OCT1, Octamer-binding transcription factor 1, OTF-1", OTF1, transcription factor 1"
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: ywwradwTwTGCAwAwtsarwm
Weblogo: 
PSSM: P0      A      C      G      T
01   0.11   0.25   0.10   0.53      y
02   0.27   0.21   0.21   0.31      w
03   0.34   0.18   0.15   0.33      w
04   0.31   0.19   0.26   0.24      r
05   0.48   0.17   0.19   0.16      a
06   0.34   0.15   0.25   0.26      d
07   0.54   0.09   0.04   0.33      w
08   0.02   0.04   0.01   0.93      T
09   0.58   0.02      0   0.40      w
10   0.01   0.02      0   0.97      T
11   0.01      0   0.78   0.21      G
12   0.21   0.78      0   0.01      C
13   0.97      0   0.02   0.01      A
14   0.40      0   0.02   0.58      w
15   0.93   0.01   0.04   0.02      A
16   0.55   0.08   0.04   0.34      w
17   0.20   0.21   0.23   0.36      t
18   0.14   0.40   0.28   0.18      s
19   0.37   0.22   0.24   0.17      a
20   0.28   0.23   0.30   0.19      r
21   0.31   0.15   0.22   0.33      w
22   0.36   0.35   0.14   0.15      m
Binding TFs: UP00399A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: ATGCAAAT
ATATTCAT
AATATGCA
AATATTCA
AATTATGC
AATTATTC
ACTAATTA
ATATGCAA
ATATGCAT
ATGAATAA
ATGCATAA
ATTAATTA
ATTATGCA
ATTATTCA
ATTTAAAT
CTAATTAA
GCTAATTA
TATGAATA
TATGCAAA
TATGCATA
			
Publications: Berger M.F, Philippakis A.A, Qureshi A.M, He F.S, Estep P.W, Bulyk M.L. Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities. Nature biotechnology 24:1429-35 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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