DNA Binding Motif

Accessions: TEAD4_PITX1_2_3_4 (HumanTF2 1.0)
Names: TEAD4_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCCtmvyTAATCC
Weblogo:
PSSM: P0 A C G T
01 183 49 162 26 r
02 58 344 26 11 C
03 344 0 16 16 A
04 0 1 1 344 T
05 177 10 67 167 w
06 25 344 96 32 C
07 5 261 10 83 C
08 86 52 83 124 t
09 101 124 68 52 m
10 93 102 93 57 v
11 43 152 49 101 y
12 54 11 0 344 T
13 344 4 22 45 A
14 344 10 0 4 A
15 0 0 108 344 T
16 21 344 73 0 C
17 32 344 21 41 C
Type: Heterodimer
Binding TFs: PITX1_TF1 / PITX1_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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