DNA Binding Motif

Accessions: TEAD4_ONECUT2 (HumanTF2 1.0)
Names: TEAD4_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rCATwCCryATYGAyy
Weblogo:
PSSM: P0 A C G T
01 1684 53 1434 57 r
02 305 3118 5 9 C
03 3118 51 212 0 A
04 23 39 62 3118 T
05 1475 16 211 3118 w
06 18 3118 42 75 C
07 49 3118 28 495 C
08 823 474 1203 618 r
09 335 1482 317 984 y
10 3118 10 7 217 A
11 512 72 12 3118 T
12 38 3118 24 1106 Y
13 14 16 3118 0 G
14 3118 13 0 14 A
15 168 1426 89 1692 y
16 278 1359 327 1155 y
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
TEAD4_TF1 (TEA/ATTS domain family)
ONECUT2_Full (Homeobox domain, CUT domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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