DNA Binding Motif

						

			
Accessions: 1hjb_ABC (3D-footprint 20231221)

			
Names: CCAAT/ENHANCER BINDING PROTEIN BETA
Organisms: Homo sapiens, Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Length: 19
Consensus: TTTCCAAAnnnTGTGGTTG
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0      0      0     96      T
03      3      3      6     84      T
04      0     96      0      0      C
05      3     87      3      3      C
06     84      6      3      3      A
07     96      0      0      0      A
08     84      3      6      3      A
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12      3      3      3     87      T
13      0      0     96      0      G
14      0      0      0     96      T
15      0      0     96      0      G
16      0      0     96      0      G
17      7      7      9     73      T
18      3      9      7     77      T
19      9      3     84      0      G
Type: Heterodimer
Binding TFs: 1hjb_B (bZIP transcription factor, Basic region leucine zipper)
1hjb_A (bZIP transcription factor, Basic region leucine zipper)
1hjb_C (Runt domain)
Binding Sites: 1hjb_G
1hjb_H
			
Publications: Tahirov T.H, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104:755-67 (2001). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.