DNA Binding Motif

Accessions: ETV5_ETV7 (HumanTF2 1.0), UN0524.1 (JASPAR 2024)
Names: ETV5_ETV7, ETV5::ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rvGGAmGGATgTCCkbg
Weblogo:
PSSM: P0 A C G T
01 118 108 159 73 r
02 136 123 153 46 v
03 4 0 458 0 G
04 1 0 458 0 G
05 458 9 4 0 A
06 273 185 0 0 m
07 0 0 458 0 G
08 3 3 458 0 G
09 458 0 0 1 A
10 20 132 4 458 T
11 124 2 323 135 g
12 41 8 11 458 T
13 8 458 5 2 C
14 3 458 7 39 C
15 93 134 458 243 k
16 74 201 257 190 b
17 68 86 200 104 g
Type: Heterodimer
Binding TFs: Q9Y603 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
ETV5_TF1 (Ets-domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9Y603
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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