DNA Binding Motif
| Accessions: | UP00069A_3 (UniPROBE 20160601), UP00101A_1 (UniPROBE 20160601) |
| Names: | Sox-1, SOX-1 protein, Sox1, SRY-box containing gene 1, Sox-12, SOX-12 protein, Sox12, SRY-box containing gene 12 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 14 |
| Consensus: | twATTGTTcthawh |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.12 0.23 0.11 0.53 t 02 0.42 0.24 0.03 0.32 w 03 0.84 0 0.01 0.14 A 04 0.01 0.01 0.01 0.97 T 05 0.02 0 0.01 0.97 T 06 0.05 0.01 0.93 0.01 G 07 0.02 0 0.01 0.97 T 08 0.04 0.06 0.02 0.88 T 09 0.23 0.42 0.18 0.17 c 10 0.16 0.11 0.07 0.66 t 11 0.29 0.26 0.20 0.25 h 12 0.57 0.11 0.11 0.22 a 13 0.42 0.15 0.09 0.34 w 14 0.27 0.28 0.20 0.25 h |
| Type: | Heterodimer |
| Binding TFs: | UP00069A (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor) UP00101A (HMG (high mobility group) box, Domain of unknown function (DUF1898)) |
| Binding Sites: | AAAACAAT AAACAAAG AAACAATT AACAAAGA AACAAAGG AACAATAA AACAATAG AACAATTG AAGACAAT AATTGTTA AATTGTTC ACAAAGAA ACAAAGGA ACAACAAT ACAATTGT AGAACAAT AGACAATA ATTGTTAA ATTGTTCA ATTGTTCG CATTGTTC CTTTGTTC GAACAATA GACAAAGA TAACAATA ATTGTCTC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
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