DNA Binding Motif

						

			
Accessions: GCM2_DLX2 (HumanTF2 1.0)

			
Names: GCM2_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rTrcGGGywadwtAATtr
Weblogo: 
PSSM: P0      A      C      G      T
01    548     98    247     40      r
02     99     71     15    795      T
03    279     43    516      0      r
04    277    795    380    187      c
05     88     28    795    135      G
06      5      0    795      1      G
07      1      4    795      0      G
08    160    298     50    286      y
09    206    171    183    235      w
10    321     96    183    195      a
11    221    161    212    201      d
12    225    144    155    270      w
13    163    233     24    795      t
14    795     64     90     57      A
15    795     16      0     11      A
16     72     27     86    795      T
17     92    150    162    795      t
18    389     22    406     76      r
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
GCM2_TF1 (GCM motif protein)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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