DNA Binding Motif

						

			
Accessions: FLI1_HOXB13_1 (HumanTF2 1.0)

			
Names: FLI1_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rccGGAArymrTwAa
Weblogo: 
PSSM: P0      A      C      G      T
01     62     22     50     34      r
02     22     75     36     25      c
03     37    111     23      8      c
04     15      5    111      0      G
05      5      0    111     13      G
06    111      7      8      8      A
07    111      6      6     35      A
08     33      9     61      8      r
09      0     49      7     63      y
10     53     31     10     18      m
11     67      3     44     23      r
12      4     14      0    111      T
13    111     33     19     73      w
14    111     13      2     16      A
15    111     29     17     10      a
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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