DNA Binding Motif

						

			
Accessions: TEAD4_FIGLA_1 (HumanTF2 1.0)

			
Names: TEAD4_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: GGwATKymCAssTG
Weblogo: 
PSSM: P0      A      C      G      T
01   1004    176   4661    370      G
02    207    389   4661    274      G
03   4661   1196    143   3498      w
04   4661      0     51     16      A
05     12    148     74   4661      T
06     14    197   3442   1219      K
07    280   1608    154   2619      y
08   1846   1259   1130    425      m
09     39   4661     21     25      C
10   4661     53     41     14      A
11     20   2290   2371     85      s
12     50   2592   2069     77      s
13      4     73     18   4661      T
14      6     20   4661      8      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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