DNA Binding Motif
| Accessions: | TrnD-Tyr (DBTBS 1.0), TrnSL-Tyr1 (DBTBS 1.0) |
| Names: | TrnD-Tyr, TrnSL-Tyr1 |
| Organisms: | Bacillus subtilis |
| Libraries: | DBTBS 1.0 1 1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed] |
| Length: | 14 |
| Consensus: | AGGGTGGTACCGCG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 2 0 0 0 A 02 0 0 2 0 G 03 0 0 2 0 G 04 0 0 2 0 G 05 0 0 0 2 T 06 0 0 2 0 G 07 0 0 2 0 G 08 0 0 0 2 T 09 2 0 0 0 A 10 0 2 0 0 C 11 0 2 0 0 C 12 0 0 2 0 G 13 0 2 0 0 C 14 0 0 2 0 G |
| Type: | Heterodimer |
| Binding TFs: | TrnD-Tyr TrnSL-Tyr1 |
| Binding Sites: | tyrS_2 / tyrS_3 tyrZ_1 / tyrZ_2 |
| Publications: | Henkin T.M, Glass B.L, Grundy F.J. Analysis of the Bacillus subtilis tyrS gene: conservation of a regulatory sequence in multiple tRNA synthetase genes. Journal of bacteriology 174:1299-306 (1992). [Pubmed] Grundy F.J, Henkin T.M. tRNA as a positive regulator of transcription antitermination in B. subtilis. Cell 74:475-82 (1993). [Pubmed] Grundy F.J, Rollins S.M, Henkin T.M. Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base. Journal of bacteriology 176:4518-26 (1994). [Pubmed] Grundy F.J, Hodil S.E, Rollins S.M, Henkin T.M. Specificity of tRNA-mRNA interactions in Bacillus subtilis tyrS antitermination. Journal of bacteriology 179:2587-94 (1997). [Pubmed] Rollins S.M, Grundy F.J, Henkin T.M. Analysis of cis-acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene. Molecular microbiology 25:411-21 (1997). [Pubmed] Grundy F.J, Collins J.A, Rollins S.M, Henkin T.M. tRNA determinants for transcription antitermination of the Bacillus subtilis tyrS gene. RNA (New York, N.Y.) 6:1131-41 (2000). [Pubmed] Gerdeman M.S, Henkin T.M, Hines J.V. In vitro structure-function studies of the Bacillus subtilis tyrS mRNA antiterminator: evidence for factor-independent tRNA acceptor stem binding specificity. Nucleic acids research 30:1065-72 (2002). [Pubmed] Grundy F.J, Moir T.R, Haldeman M.T, Henkin T.M. Sequence requirements for terminators and antiterminators in the T box transcription antitermination system: disparity between conservation and functional requirements. Nucleic acids research 30:1646-55 (2002). [Pubmed] |
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