DNA Binding Motif

						

			
Accessions: GCM2_HOXA13 (HumanTF2 1.0), UN0553.1 (JASPAR 2024)

			
Names: GCM2_HOXA13, GCM2::HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: ATRCGGGTaATAAAa
Weblogo: 
PSSM: P0      A      C      G      T
01   5476    695   1108    191      A
02    215    122     72   7121      T
03   1924     92   5208     39      R
04    973   5940    798    653      C
05    157     37   7104     60      G
06      0      0   7191      0      G
07      0      0   7186      0      G
08     84    782    140   6984      T
09   6107   1975    190    837      a
10   7063    356    471    629      A
11    279    366    584   7103      T
12   6742    345    953   1602      A
13   7045    297    356    835      A
14   6817    624    648    726      A
15   3604   1656    989    936      a
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
HOXA13_TF2 / P31271 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
P31271
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.