DNA Binding Motif

						

			
Accessions: 4mhg_A (3D-footprint 20231221)

			
Names: Transcription factor ETV6
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ETV6 bound to a specific DNA sequence
Length: 8
Consensus: anCCGGAA
Weblogo: 
PSSM: P0      A      C      G      T
01     54     13     16     13      a
02     24     24     24     24      n
03      0     96      0      0      C
04      0     83      0     13      C
05      0      0     96      0      G
06      0      0     96      0      G
07     68      0     13     15      A
08     96      0      0      0      A
Binding TFs: 4mhg_A (Ets-domain)
Binding Sites: 4mhg_B
4mhg_C
			
Publications: De S, Chan A.C, Coyne H.J, Bhachech N, Hermsdorf U, Okon M, Murphy M.E, Graves B.J, McIntosh L.P. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. Journal of molecular biology 426:1390-406 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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