DNA Binding Motif

Accessions: GCM1_FIGLA_2_3_4_5 (HumanTF2 1.0)
Names: GCM1_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: CAssTGkkgggsrTGcGGG
Weblogo:
PSSM: P0 A C G T
01 92 1391 79 95 C
02 1391 63 147 62 A
03 4 482 909 77 s
04 20 472 918 41 s
05 50 51 108 1391 T
06 44 32 1391 24 G
07 121 237 646 386 k
08 300 210 413 469 k
09 335 283 498 275 g
10 326 266 473 326 g
11 300 267 481 343 g
12 226 354 562 248 s
13 635 256 446 54 r
14 154 231 179 1391 T
15 430 108 1391 24 G
16 425 1391 423 455 c
17 161 47 1391 397 G
18 44 39 1391 86 G
19 35 20 1391 24 G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM1_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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